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Effect of perioperative vitamin B6 on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery

Effect of perioperative vitamin B6 on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065254
Enrollment
Unknown
Registered
2022-11-01
Start date
2022-11-01
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative nausea and vomiting

Interventions

Experimental group:Administere vitamin B6 during the perioperative period
The control group:Use the same volume of normal saline during the perioperative period

Sponsors

Department of Anesthesiology of the Third Xiangya Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Gynecology, Elective, General anesthesia, Laparoscopy; 2. Aged 18-65 years; 3. ASA I - III level; 4. BMI 18.5-24.9 kg/m; 5. Non-smoker.

Exclusion criteria

Exclusion criteria: 1. He was known to be allergic to vitamin B6 and had taken VB6 one week before admission; 2. Had taken antiemetics, emetogenic drugs, opioids or glucocorticoids within one week before surgery, or had used opioids for a long time; 3. Suffer from other diseases that may present as nausea or vomiting, such as hepatitis or gastrointestinal diseases; Pregnancy or lactation; Mental retardation, mental illness or neurological disease; 4. Refusing to cooperate with the trial patient; 5. No return visit within one day after operation; 6. Regional nerve block and total intravenous anesthesia were used; 7. Patients who did not undergo elective surgery as planned.

Design outcomes

Primary

MeasureTime frame
postoperative nausea and vomiting;

Secondary

MeasureTime frame
The time of the first vomit;The degree of nausea;

Countries

China

Contacts

Public ContactYuan Le

the Third Xiangya Hospital of Central South University

leyuanxy@csu.edu.cn+86 13787107617

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026