acute postoperative pain
Conditions
Interventions
RNK1:Esketamine + Ropivacaine
RNK2:Esketamine + Ropivacaine
RNK3:Esketamine + Ropivacaine
R: Ropivacaine
Sponsors
The General Hospital of Northen Theater Command
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ASA grade I-II; age >= 18 years old, no gender restrictions; patients admitted to the General Hospital of the Northern Theater for elective knee arthroscopic surgery under general anesthesia; voluntarily signed the informed consent.
Exclusion criteria
Exclusion criteria: 1 ) known to be allergic to research drugs or belong to susceptible populations ; 2 ) Peripheral neuropathy or injury ; 3 ) Have a history of chronic pain ; 4 ) with severe cardiovascular and cerebrovascular diseases, respiratory diseases, blood diseases, endocrine diseases or liver and kidney dysfunction ; 5 ) have elevated blood pressure, intraocular pressure ( such as glaucoma ), increased intracranial pressure risk ; 6 ) Patients who underwent surgery or used experimental drugs within one week before surgery ; 7 ) Communication disorders ( reading and writing Chinese obstacles, language barriers, visual impairment or hearing impairment, etc. ) can not cooperate to complete the study ; 8 ) combined neurological or mental illness ; 9 ) Refusing to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of sensory block; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative pain score;Postoperative recovery quality score;oaa/s score; | — |
Countries
China
Contacts
Public ContactYingjie Sun
The General Hospital of Northen Theater Command
Outcome results
None listed