Autism spectrum disorders
Conditions
Interventions
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
7 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1.Subjects and their guardians must sign the study informed consent form prior to initiating any research-related procedures. 2.Aged 7–18 years, regardless of gender. 3.Meet the diagnostic criteria for Autism Spectrum Disorder (ASD) as outlined in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). 4.Disease duration =5 years, with no significant improvement in overall symptoms compared with baseline after at least 6 months of two or more standardized behavioral interventions, as determined by rigorous and standardized assessments. 5.Patients or guardians must be capable of adequate communication and willing to fully cooperate with the study protocol, including completing required examinations, follow-up visits, and related agreements.
Exclusion criteria
Exclusion criteria: 1.Participants must not have been diagnosed with panic disorder, post-traumatic stress disorder, eating disorders, substance use disorder, or substance dependence within the 6 months prior to screening. 2.Participants with contraindications to surgery, such as significant medical comorbidities or inability to discontinue anticoagulant therapy. 3.Preoperative brain magnetic resonance imaging reveals significant structural abnormalities. 4.Those who have had cochlear implants, pacemakers, defibrillators, previously implanted unilateral or bilateral similar devices, or have undergone other surgical procedures within the past six months that the investigator believes may affect the study. 5.Currently participating in or have participated in other drug or medical device clinical trials within 3 months before screening. 6.Other individuals deemed unsuitable for participation in this clinical study by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the safety of therapy; | — |
Secondary
| Measure | Time frame |
|---|---|
| the remission rate of neuropsychological tests;Adverse events; | — |
Countries
China
Contacts
Public ContactWang Wei
Department of Neurosurgery, West China Hospital
Outcome results
None listed