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Study on influencing factors of swallowing function in healthy people and dysphagia patients after stroke and the effect of swallowing rehabilitation therapy about brain function based on functional near-infrared spectroscopy

Study on influencing factors of swallowing function in healthy people and dysphagia patients after stroke and the effect of swallowing rehabilitation therapy about brain function based on functional near-infrared spectroscopy

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065153
Enrollment
Unknown
Registered
2022-10-29
Start date
2022-10-28
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

conventional treatment:conventional swallowing training
iTBS:intermittent theta burst stimulation

Sponsors

Affiliated Hospital of Guizhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Healthy subjects: aged 18-85 years; A history of speech dysarthria, known otorhinolaryngologic disease, pulmonary or neurological disease, or structural abnormalities was excluded by questionnaire. Have not recently taken any medication affecting swallowing function; No previous history of head, neck, gastroesophageal surgery; VFSS examination ruled out swallowing dysfunction. Dysphagia patients after stroke: ? unilateral primary cerebral infarction, confirmed by head CT or MR; ? Diagnosis of dysphagia by VFSS; ? Age between 18 and 85 years old; ? The duration of the disease was between 2 weeks and 2 months; ? Vital signs were stable, abbreviated mental test scale (AMTS) score >7; ? Patients and their families are willing to sign informed consent.

Exclusion criteria

Exclusion criteria: Dysphagia patients after stroke:? patients with malignant tumors; ? Serious medical diseases and other neurological diseases; (3) Mental disorders or cognitive dysfunction; ? Patients with dysphagia after non-cerebral infarction; (5) Patients who had undergone head and neck surgery and gastroesophageal surgery.

Design outcomes

Primary

MeasureTime frame
VFSS quantitative analysis: Movement distance of hyoid lift and advance;MBSImP scale;surface electromyography:Mean values of swallowing duration and maximum amplitude of bilateral suprhyoid muscle groups;Motor evoked potential;Mean HbO of bilateral IGF region, SMC region and SMA region;

Countries

China

Contacts

Public ContactQian Zhang

Affiliated Hospital of Guizhou Medical University

28848471@qq.com13037880521

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026