Skip to content

The efficacy and safety of remifentanil and lidocaine administration via different endotracheal tubes in early administration of oral fluid following general anesthesia: a single centre , randomized study

The efficacy and safety of remifentanil and lidocaine administration via different endotracheal tubes in early administration of oral fluid following general anesthesia: a single centre , randomized study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065136
Enrollment
Unknown
Registered
2022-10-28
Start date
2022-10-31
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cough related with endotracheal tube

Interventions

L1 group:2% lidocaine administration via the perforated outer cuff of a dual-cuff endotracheal tube
L2 group:2% lidocaine administration onto the upper and lower of glottis

Sponsors

Guangdong Provincial Hospital of Tradition Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) Age 18-65 years old, BMI 18.5-24;2) American Society of Anesthesiologists (ASA) Classification: I-II;3) Elective endotracheal intubation and general anesthesia Elective surgery is as follows: lower abdominal surgery -- laparoscopic hysterectomy or oophorectomy, inguinal hernia repair;Urology -- spermatic vein ligation, percutaneous nephrolithotomy;Department of Breast - mastectomy;Orthopedic -- lumbar fusion, knee joint, shoulder joint, hip joint 4) Obtain informed consent from the patient and/or legal guardian and sign informed consent;

Exclusion criteria

Exclusion criteria: 1) Common diseases causing dysphagia include oropharyngeal and esophageal diseases; 2) Mental disorder, inability to communicate, difficult airway, high risk of reflux and aspiration during perioperative period; 3) History of chronic respiratory diseases (such as chronic obstructive pulmonary disease or asthma), respiratory and lung infections within 2 weeks, chronic cough, and smoking within 48 hours before surgery 4) Serious cardiovascular, cerebrovascular, liver or kidney diseases 5) Previous laryngeal or tracheal surgery, local anesthetic allergy, and treatment with beta-blockers 6) Nasogastric tube was inserted during perioperative period 7) Digestive diseases such as hiatal hernia and gastroesophageal reflux should not be consumed immediately after surgery due to anesthesia or surgical factors

Design outcomes

Primary

MeasureTime frame
cough;

Secondary

MeasureTime frame
Other secondary indicators;

Countries

China

Contacts

Public ContactPing Li

Guangdong Provincial Hospital of Tradition Chinese Medicine

346036322@qq.com+8615622149528

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026