Comparative effectiveness of different surgical timing on neurological outcomes for cranioplasty

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200065127

Enrollment

Unknown

Registered

2022-10-28

Start date

2023-01-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cranioplasty

Interventions

early cranioplasty:None

delayed cranioplsty:None

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Age:18 Years to 65 Years; 2.Cranial defect(due to traumatic brain, stroke, infiltrative tumour and so on); 3.The defect size is over 25cm2; 4.Cranioplasty is feasible according to doctor's evaluation; 5.Patient or their legally authorized representative (LAR) has provided written informed consent.

Exclusion criteria

Exclusion criteria: 1.With unhealed scalp; 2.With uncontrolled intracranial infection or intracranial hematoma is not cured; 3.Poor general condition; 4.Untreated hydrocephalus.

Design outcomes

Primary

Measure	Time frame
Barthel index;Functional Independence Measure;	—

Secondary

Measure	Time frame
Glasgow outcome scale (GOS);Complications Rates:including seizure, hematoma, hydrocephalus, etc.;	—

Countries

China

Contacts

Public ContactJunwen Guan

West China Hospital, Sichuan University

guanjunwen_scu@163.com18981381916

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026