Gastrointestinal (GI) Malignancies
Conditions
Interventions
Gold Standard:The histopathological report of sample
Index test:Peripheral blood's metabolic, 5mC & 5hmC profiling
Sponsors
The Fourth Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. The age is 18 years old and above, and the gender is not limited; 2. Patients with gastrointestinal tumor resection surgery; 3. There is no other malignant tumor disease history within 5 years, and no anti -cancer treatment has been received before surgery (local or system); 4. Postoperative pathological diagnosis is clear; 5. Voluntary signing of informed consent.
Exclusion criteria
Exclusion criteria: 1. It is impossible to perform gastroscopy due to gastrointestinal discomfort; 2. At present, other inappropriate surgery or multiple tumors coexist; 3. One month before the group received blood transfusion treatment, or there is a history of alcoholism and drug abuse; 4. Patients who cannot obtain enough blood specimen ( >=12ml); 5. There are anemia, fever, low self -immunity, incomplete coagulation function, etc. 6. Patients with autoimmune diseases and blood system diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peripheral blood's metabolic profiling;cfDNA 5mC;cfDNA-5hmC; | — |
Countries
China
Contacts
Public ContactLu Zhen
The Fourth Affiliated Hospital of Anhui Medical University
Outcome results
None listed