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Research on the efficacy and brain function of concentrated intensive cognitive behavioral therapy for patients with Obsessive-Compulsive Disorder

Research on the efficacy and brain function of concentrated intensive cognitive behavioral therapy for patients with Obsessive-Compulsive Disorder

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065073
Enrollment
Unknown
Registered
2022-10-27
Start date
2022-10-31
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obsessive compulsive disorder

Interventions

treatment group:concentrated intensive CBT plus traditional medicine
TAU group:traditional medicine

Sponsors

Beijing Anding Hospital Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Fulfilled the criteria for OCD in the diagnostic and Statistical Manual of mental disorders, 5th Edition (DSM-5) (2) Yale Brown Obsessive Compulsive Scale (Y-BOCS) total score > 16 (3) Age: 18 ~ 45 years old, right-handed, junior high school education or above (4) Diagnosed pollution / cleaning and examination as the main symptoms by two psychiatrists with professional titles of attending physician and above (5) In the first 4 weeks of enrollment, the drug treatment was stable without drug adjustment (6) Provided informed written consent.

Exclusion criteria

Exclusion criteria: (1) Patients have a neurological illness or major physical diseases (2) Fulfilled the criteria for schizophrenia, bipolar disorder, depressive disorder, Tourette syndrome, personality disorder and other mental disorders (3) Patients who are drug abuse and psychoactive substances (4) Patients who have received systematic CBT in the past (5) Patients who are not MRI compatible

Design outcomes

Primary

MeasureTime frame
Yale-Brown Obsessive-Compulsive Scale;

Secondary

MeasureTime frame
Beck Anxiety Inventory;Beck Depression Inventory;the MOS item short from health survey;Obsessive Belief Questionnaire-44;Cognitive Emotion Regulation Questionnaire-Chinese Version;rs-fMRI;

Countries

China

Contacts

Public ContactLixiaohong

Beijing Anding Hospital Affiliated to Capital Medical University

lxhshy2002@163.com83024533

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026