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Explore the relationship between the content of short chain fatty acid (SCFA) and vascular regeneration after ischemic stroke

Explore the relationship between the content of short chain fatty acid (SCFA) and vascular regeneration after ischemic stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200065052
Enrollment
Unknown
Registered
2022-10-26
Start date
2022-10-30
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Minor stroke group (NIHSS<=4):none
moderate stroke group (5<=NIHSS<=15):none
moderate-severe stroke group (16<=NIHSS<=20):none
severe stroke group (21<=NIHSS<=42),:none
control group (healthy adults):none

Sponsors

The Second Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 74 Years

Inclusion criteria

Inclusion criteria: 1) Age 18 and above, under 75; Both sexes; 2) Diagnosed as ischemic stroke by imaging methods such as CT or magnetic resonance imaging (MRI), and diagnosed as ischemic stroke by a neurologist. 3) Understand and voluntarily sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1) Patients with a history of ischemic stroke and/or lacunar infarction, combined with sequelae such as cognitive impairment and limb disorders; 2) Cranial imaging examination confirmed the presence of diseases causing similar symptoms, such as brain tumors, encephalitis, brain abscesses, or confirmed hemorrhagic cerebral infarction, epidural hematoma, etc.; 3) Patients with severe heart disease, severe arrhythmia or heart failure; 4) Patients with severe abnormal liver and kidney function (liver function laboratory indexes ALT> 80U/L, renal function laboratory index Male: Cr> 200umol/L, female: Cr> 145.5 u mol/L); 5) Patients with a history of mental illness or dementia; 6) Significant drug or alcohol abuse; 7) Allergies and allergies to two or more drugs or foods; Or is known to be allergic to the ingredient; 8) Women who are pregnant, planning to be pregnant or breastfeeding; 9) Participated in other clinical trials in the past 3 months; 10) Patients deemed ineligible for this study by the investigator.

Design outcomes

Primary

MeasureTime frame
Short chain fatty acid;blood fat;Glycosylated hemoglobin;Vascular endothelial growth factor;Basic fibroblast growth factor;Angiopoietin;CD34+;

Countries

China

Contacts

Public ContactXiangjian Zhang

The Second Hospital of Hebei Medical University

zhang6xj@aliyun.com15732189189

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026