AML
Conditions
Interventions
ADR:Drug withdrawal
Control group:N/A
Sponsors
Shenzhen Longhua District Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: inclusion criteria: (1) The dose of voriconazole was administered according to the commonly used clinical standard, and the loading dose (day 1): oral tablets were 0.4 g (>= 40 kg), 0.2 g (= 40 kg), 0.1 g (< 40 kg) for oral tablets, q12h. (2) Voriconazole concentration (VRC) and voriconazole-n-oxide concentration (N-oxide VRC) were measured within 5-7 days after voriconazole administration. The above blood samples are from the blood drug concentration monitoring of the remaining samples used by the Department of Hematology when the patients were hospitalized to check the biochemical indicators, so as to avoid the patients from being traumatized again.
Exclusion criteria
Exclusion criteria: exclusion criteria: (1) Patient age 34.2 umol/L) (8) Patients with chronic active inflammatory disease (CRP > 5 mg/dl); as well as (9) Patients with poor drug compliance based on electronic medical records.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alanine aminotransferase;Aspartate aminotransferase; | — |
Countries
China
Contacts
Public ContactXiaokang Wang
Shenzhen Longhua District Central Hospital
Outcome results
None listed