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Clinical observation of broad-spectrum antibiotics combined with nitroimidazoles in the treatment of postoperative abdominal infection

Clinical observation of broad-spectrum antibiotics combined with nitroimidazoles in the treatment of postoperative abdominal infection

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200065007
Enrollment
Unknown
Registered
2022-10-25
Start date
2022-07-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative abdominal infection

Interventions

Broad-spectrum antibiotics (BSA):None
Nitroimidazoles combined with broad-spectrum antibiotics (NCBSA):None

Sponsors

General Hospital of Southern Theatre Command
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Adult patients aged 18 years or older with uncomplicated and complicated abdominal infection after operation, that is, they have clinical manifestations such as abdominal pain or systemic inflammatory reaction, and the infection focus is confined in the gastrointestinal tract wall or penetrates the abdominal cavity organs and enters the peritoneum, accompanied by peritonitis or abdominal abscess formation.

Exclusion criteria

Exclusion criteria: 1. Patients with advanced tumor; 2. Non-intravenous administration to patients with nitroimidazole drugs; 3. Patients who only use nitroimidazole drugs in anti-infection program.

Design outcomes

Primary

MeasureTime frame
28-day mortality;Routine blood test;Procalcitonin;C- reactive protein;Temperature;APECH II score;SOFA score;—

Countries

China

Contacts

Public ContactHongyi Liang

General Hospital of Southern Theatre Command

532875210@qq.com+86 18922413801

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026