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Comparative Effectiveness of Low-fluence 755nm Picosecond Laser with A Diffractive Lens Array for Treatment of Post-inflammatory Hyperpigmentation, A Randomized, Split-Lesion Clinical Trial

Comparative Effectiveness of Low-fluence 755nm Picosecond Laser with A Diffractive Lens Array for Treatment of Post-inflammatory Hyperpigmentation, A Randomized, Split-Lesion Clinical Trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065003
Enrollment
Unknown
Registered
2022-10-25
Start date
2022-10-25
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-inflammatory hyperpigmentation

Interventions

A:Honeycomb picosecond therapy
B:Large spot low energy Q1064 laser

Sponsors

Shanghai Jiao Tong University School of Medicine,Shanghai Ninth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients with freckles, aged 18-60, of both sexes; 2. Never received relevant treatment before; 3. After fully understanding the treatment plan and risks, voluntarily signed the informed consent, and was willing to accept my own controlled test and cooperate with follow-up.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Allergic to topical anesthetics; 3. Any active skin disease in the test area; 4. Patients with wound, infection, or epidermal rupture at the test site; 5. No PIH occurred after treatment; 6. Other factors that the investigator believes may have influenced the results of the trial.

Design outcomes

Primary

MeasureTime frame
Pigmentaion index;

Secondary

MeasureTime frame
Patient satisfaction rate;Reflectance confocal microscopy, RCM;

Countries

China

Contacts

Public ContactZhen Zhang

Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine

zz6503@vip.126.com+86 13817594541

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026