wet age-related macular degeneration
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 50 years and meeting the diagnostic criteria for wet AMD; 2. OCTA suggesting the presence of subretinal neovascularization; 3. No prior treatment (anti-VEGF, PDT, etc.); 4. Best-corrected visual acuity (BCVA) between 5-75 letters in the study eye.
Exclusion criteria
Exclusion criteria: 1. Allergy to drugs needed in the diagnosis and treatment; 2. A history of internal eye surgery (except surgery about cataract), trauma or fundus laser photocoagulation; 3. Other ophthalmologic diseases besides wAMD or cataracts; 4. Renal insufficiency and serious cardiovascular and cerebrovascular diseases; 5. Surgery required due to vitreous hemorrhage during follow-up treatment; 6. Recent preparation for childbirth, pregnancy or lactation; 7. Poor compliance with diagnosis and treatment or difficulty conducting regular outpatient review and cooperating with treatment.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| central retinal thickness;last injection interval;number of injections; | — |
Primary
| Measure | Time frame |
|---|---|
| The best-corrected visual acuity; | — |
Countries
China
Contacts
The First Affiliated Hospital of Chongqing Medical University