incisional hernia
Conditions
Interventions
Intervention group:ileostomy closure + biological mesh placement
Control group:ileostomy closure
Sponsors
Shanghai Jiaotong University School of Medicine, Renji Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-80 years old with definitive rectal cancer resected requiring prophylactic stoma retraction and assessed by image-based deep learning model as having high risk factors for incisional hernia; 2. Resectable tumor and without distant metastasis (cT1-3N1-2M0) as assessed by CT, MRI and other examinations; 3. Patients who had exclusion criteria but were downstaged by neoadjuvant chemotherapy could be included; 4. Having detailed and complete data of previous surgery and postoperative adjuvant therapy (including but not limited to detailed clinical data such as previous surgery admission record, surgery record, discharge summary, preoperative and postoperative follow-up CT of previous surgery, postoperative radiotherapy time and regimen); 5. Those who voluntarily participate in this study can follow up as required and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Transendoscopic local excision is feasible at stage T1; 2. Previous surgical history of rectal cancer, pregnancy, ASA > III, emergency surgery, and other surgeries at the same time; 3. Combined important organ dysfunction cannot tolerate surgery; 4. Those who cannot accept porcine-derived devices due to religion, ethnicity and other issues; 5. Subjects who are considered by the investigator to be unsuitable for this clinic; 6. Those with combined mental illness or those who cannot cooperate with the corresponding diagnosis and treatment follow-up. ollow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of incision hernia after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of incisional infection;incidence of incisional local pain;incidence of incisional seroma; | — |
Countries
China
Contacts
Public ContactZizhen Zhang
Shanghai Jiaotong University School of Medicine, Renji Hospital
Outcome results
None listed