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Effects of remimazolam and sevoflurane on postoperative delirium and early postoperative cognitive dysfunction in elderly patients

Effects of remimazolam and sevoflurane on postoperative delirium and early postoperative cognitive dysfunction in elderly patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064984
Enrollment
Unknown
Registered
2022-10-25
Start date
2022-11-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Effects of remimazolam and sevoflurane on postoperative delirium and early postoperative cognitive dysfunction in elderly patients

Interventions

Group 1:remimazolam
Group 2:sevoflurane
Group 3:remimazolam and sevoflurane

Sponsors

Taian City Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 65 years old; 2. ASA grade I-III; 3. Patients who undergo elective laparoscopic-assisted gastrointestinal surgery in our hospital.

Exclusion criteria

Exclusion criteria: 1. Combined with serious diseases of cardiovascular, respiratory, liver, kidney or central nervous system; 2. Cognitive dysfunction or delirium existed before operation; 3. History of dementia or mental illness; 4. Currently using sedatives, antidepressants or corticosteroids; 5. Alcoholism and drug dependence; 6. Difficulty in follow-up or poor compliance (such as aphasia, blindness, etc.); 7. Combined with experimental drug contraindications.

Design outcomes

Primary

MeasureTime frame
Incidence of postoperative delirium;—

Countries

China

Contacts

Public ContactShenqiang Gao

Taian City Central Hospital

gaoshenqiang1979@sina.com+86 13563806165

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026