obese
Conditions
Interventions
group 1:lidocaine (1.5 mg/kg) was injected intravenously before intubation
group 2:the same amount of normal saline was injected intravenously before intubation
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients who underwent laparoscopic vertical (sloraleve) gastrectomy under general anesthesia through video laryngoscope for oral endotracheal intubation in the Affiliated Hospital of North Sichuan Medical College. The inclusion criteria were: body mass index (BMI) >= 30 kg/m2, ASA II-III, age 18 -60 years old.
Exclusion criteria
Exclusion criteria: 1. Severe cardiopulmonary disease; 2. Abnormal liver and kidney function; 3. Body weight > 150 Kg (not suitable for Marsh model propofol target-controlled infusion); 4. Patients with difficult airway; 5. Those who are allergic to general anesthetics or lidocaine; 6. History of drug or alcohol abuse; 7. Recently used drugs that affect the sympathetic adrenergic system or hemodynamics; 8. Pregnant or lactating women; 9. Persons with neuropsychiatric disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mean arterial pressure (MAP);heart rate (HR); | — |
Secondary
| Measure | Time frame |
|---|---|
| systolic blood pressure (SBP);diastolic blood pressure (DBP);Set value of sufentanil effect site concentration;sufentanil dosage during the test;propofol dosage during the test;rocuronium dosage during the test;lidocaine dosage during the test;infusion volume during the test; | — |
Countries
China
Contacts
Public ContactFaping Tu
Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed