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Effect of Obstructive Sleep Apnea on Postoperative Delirium and Its Possible Mechanisms

Effect of Obstructive Sleep Apnea on Postoperative Delirium and Its Possible Mechanisms

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200064978
Enrollment
Unknown
Registered
2022-10-25
Start date
2019-01-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive Sleep Apnea

Interventions

None listed

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 84 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 65 years old; 2. Hospitalization time >= 3 days; 3. Elective surgery; 4. Barrier-free communication; 5. Physical condition suitable for assessment; 6. Voluntarily participate in the research and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Those with depression or cognitive impairment (MMSE < 20 points); 2. Persons with infectious diseases who need to be isolated (such as tuberculosis, AIDS, hepatitis A, etc.); 3. People with low immune function who need protective isolation (such as leukemia, etc.); 4. Patients with multiple metastases or chemotherapy alone; 5. Those who are transferred or discharged without treatment; 6. Exploratory laparotomy for multiple metastases found during surgery; 7. Sudden deterioration of the condition cannot be evaluated (such as sudden coma, mental disorder with agitation or risky behavior, multiple organ failure and systemic infection, etc.).

Design outcomes

Primary

MeasureTime frame
incidence of postoperative delirium;incidence of postoperative cognitive disorder;incidence of postoperative cognitive disorder;sleep disturbance;symptom of OSA;Blood routine and blood biochemistry;inflammatory biomarker;brain injury;postoperative complications;postoperative recovery status;Intraoperative risk events;

Countries

China

Contacts

Public ContactYanyan Wang

Department of Science and Technology, West China Hospital, Sichuan University

kittyanwang@gmail.com+86 18140052755

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026