Climacteric syndrome
Conditions
Interventions
Group 1:modified xiaoyao pill
Group 2:Xiangshao Granules
Sponsors
Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Conforming to the diagnostic criteria of western medicine for menopausal (menopausal) syndrome; 2. It conforms to the syndrome differentiation standard of liver depression and fire; 3. The course of disease shall not exceed 24 months; 4. The total score of domestic improved Kupperman >= 15; 5. The score of Beck Self Rating Depression Scale (BDI) was 5-15; 6. The score of Beck Self Rating Anxiety Scale (BAI) is 15-35; 7. Sign the informed consent form voluntarily.
Exclusion criteria
Exclusion criteria: 1. History of endometrial hyperplasia or vaginal bleeding with unknown cause; 2. Known or suspected pregnancy; 3. Those suffering from thrombotic disease in the last six months; 4. Known patients with serious primary diseases such as heart, cerebrovascular, liver, kidney and hematopoietic system, diabetes, thyroid disease, malignant tumor, and psychosis; 5. Severe liver and kidney dysfunction; 6. Those who have participated in other clinical researches in the past month, or who have used relevant Chinese and western medicines to treat the disease in the past month, so that the drug effect cannot be judged; 7. Those allergic to the test drug; 8. Suspected or confirmed to have a history of alcohol addiction and drug abuse, or other diseases or conditions that, according to the judgment of the researcher, reduce the possibility of enrollment or complicate enrollment, such as frequent changes in the working environment, unstable living environment and other conditions that are likely to cause loss of follow-up; 9. The investigator thinks it is not suitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM syndrome integral table;Improved Kupperman Rating Scale in China; | — |
Secondary
| Measure | Time frame |
|---|---|
| MENQOL scale;Beck Depression Inventory;Beck Anxiety Inventory;Four sex hormones (estradiol, follicle stimulating hormone, luteinizing hormone, progesterone);anti-mullerian hormone;Inhibin B;Central neurotransmitters (5-HT, DA); | — |
Countries
China
Contacts
Public ContactLing Tang
Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine
Outcome results
None listed