Serum proteomics of cognitive dysfunction after heart valve replacement under cardiopulmonary bypass

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200064929

Enrollment

Unknown

Registered

2022-10-23

Start date

2022-10-22

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive dysfunction after heart valve replacement

Interventions

Group 1:

Eligibility

Sex/Gender

All

Age

45 Years to 74 Years

Inclusion criteria

Inclusion criteria: 1. Age: 45-64 years old; 2. ASA I-III level; 3. Cardiac valve replacement under CPB; 4. The informed consent form has been signed.

Exclusion criteria

Exclusion criteria: 1. History of cerebrovascular, epilepsy and other central nervous system diseases, endocrine or metabolic disorders; 2. History of dementia, neurological or psychiatric diseases caused by various reasons; 3. There is a language barrier, severe hearing or visual impairment, and a history of alcoholism; 4. Currently using opioids, glucocorticoids or other hormones, and sedatives for treatment.

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative cognitive dysfunction;	—

Countries

China

Contacts

Public ContactWang Haiying

Zunyi Medical University

2371827590@qq.com.cn+86 18685268901

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026