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Half effective-site concentration of remifentanil combined with remimazolam besylate in hysteroscopy

Half effective-site concentration of remifentanil combined with remimazolam besylate in hysteroscopy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064885
Enrollment
Unknown
Registered
2022-10-20
Start date
2022-10-20
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abnormal uterine bleeding

Interventions

Experimental group:Pump remifentanil

Sponsors

Mengcheng County No. 1 People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1. The subjects voluntarily participated and signed the informed consent; 2. Subjects aged 18-64 years; 3. The subjects were classified as I-II by ASA; 4. Subjects with body mass index (BMI) of 18.5-24.9 kg / m^2; 5. Subjects scheduled for hysteroscopy.

Exclusion criteria

Exclusion criteria: 1. Those with a history of alcoholism, long-term use of sedative and analgesic drugs or or allergy to general anesthesia drugs; 2. Severe obstructive sleep apnea; 3. Uncontrolled severe high blood pressure; 4. Moderate to severe anemia(Hb<=90g/L); 5. Emergency patients or patients with acute inflammation; 6. Patients with impaired liver or kidney function; 7. Mental illness or neurological disease, dementia or severe cognitive impairment; 8. Any patient of communication difficulties; 9. Pregnant and lactating patients.

Design outcomes

Primary

MeasureTime frame
Recording the operation time;Recovery time of the patient (time from the end of the operation to the time of opening the eyes);The number of patients with SpO2 < 90%;Postoperative PACU stay time;Sedative drug dosage;Analgesic dosage;

Secondary

MeasureTime frame
The changes of systolic blood pressure, diastolic blood pressure, heart rate, BIS score and SpO2 were observed and recorded before anesthesia (T0), 2 minutes after anesthesia (T1), at the time of cervical dilatation (T2), at the end of operation (T3) and at the time of recovery (T4);The visual analogue scale (VAS) of lower abdominal pain was recorded immediately after awake and 15 min, 30 min, 1 h, 2 h and 6 h after operation;The number of patients using ephedrine and atropine in each group was recorded;

Countries

China

Contacts

Public ContactZhang Xiaoqiang

Mengcheng County No. 1 People's Hospital

zxqahl@126.com+86 13309670321

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026