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A study on the neural network regulation mechanism of personalized tDCS in prolonged disorders of consciousness based on electric field modeling

A study on the neural network regulation mechanism of personalized tDCS in prolonged disorders of consciousness based on electric field modeling

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064873
Enrollment
Unknown
Registered
2022-10-20
Start date
2022-10-20
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

disorders of consciousness

Interventions

t-tDCS group:trandicional tDCS
p-tDCS group:personalized tDCS

Sponsors

Zhejiang Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Conformed to MCS international diagnostic criteria formulated by Giacino in 2002 or UWS diagnostic criteria proposed by Laureys in 2010; 2. The course of disease is more than 1 month; 3. No sedative or antiepileptic drugs were used in the past 1 month; 4. No skull defect or skull repair; 5. No obvious cerebral edema or severe cerebral atrophy; 6. No magnetic resonance examination contraindications; 7. Family members sign informed consent form.

Exclusion criteria

Exclusion criteria: 1. Previous history of neurological or psychiatric disorders; 2. Previous history of cerebral ischemia or cerebral hemorrhage; 3. Have a history of tumor; 4. Have taken sedative drugs or antiepileptic drugs in the past 1 month; 5. Unstable vital signs.

Design outcomes

Primary

MeasureTime frame
Functional imaging;Modified Coma Recovery Scale;Simple Assessment of Disturbance of Consciousness;Motor Behavior Tools Revised Edition;Extended Glasgow Outcome Scale;Disability Rating Scale;

Countries

China

Contacts

Public ContactZhang Li

Zhejiang Provincial People's Hospital

953462719@qq.com+86 13732274598

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026