Helicobacter pylori infection
Conditions
Interventions
control group:placebo
Sponsors
Army Medical Center of PLA
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Adults aged 18-70 years, no gender limit; 2. Patients diagnosed with chronic gastritis (including atrophic gastritis and non-atrophic gastritis) by gastroscopy in outpatient department were positive by at least two tests: 13C -Urea breath test (13C-UBT), Rapid urease test (RUT) or H.pylori found by histological examination of gastric mucosa; 3. Never received HP eradication treatment before.
Exclusion criteria
Exclusion criteria: 1. Used PPI, P-CAB, H2 receptor antagonists, antibiotics, bismuth, probiotics and other drugs within three months before treatment; 2. Patients who are allergic to the drugs used in this study; 3. There are serious concomitant diseases or malignant tumors; 4. History of colonoscopy, use of laxatives or acute gastroenteritis within 4 weeks prior to treatment; 5. Unhealed gastric ulcer or duodenal bulbous ulcer; 6. Pregnant or lactating patients; 7. Patients with previous gastric and esophageal surgery; 8. Those who cannot sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| H.pylori infection eradication rate;Intestinal microbiome sample;Gastric microbiome sample; | — |
Secondary
| Measure | Time frame |
|---|---|
| Treat digestive tract symptoms before and after treatment;Adverse event; | — |
Countries
China
Contacts
Public ContactLan Chunhui
Army Medical Center of PLA
Outcome results
None listed