The Efficacy of Various Dose of Low-dose Naloxone on Postoperative Recovery in Sufentanil-treated Patients

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200064865

Enrollment

Unknown

Registered

2022-10-20

Start date

2022-04-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group N1:High Dose Naloxone Treatment

Group N2:Lowe Dose Naloxone Treatment

Control group:Saline Treatment

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients aged >= 18 years, ASA class I to III, who were intended to undergo laparoscopic surgery under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Emergency operation, preoperative intestinal obstruction, gastroesophageal reflux disease, gastric retention and other diseases; 2. Opioid analgesics or antiemetic drugs were used before surgery; 3. Patients with moderate to severe cardiopulmonary dysfunction or obvious abnormal liver and kidney function; 4. Patients undergoing laparotomy, cannot provide informed consent.

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative nausea and vomiting;Respiratory depression;Delayed awakening;	—

Countries

China

Contacts

Public ContactZhang Xin

Wuxi People's Hospital

xinzhang3@njmu.edu.cn+86 13818832760

Outcome results