Postpartum Depression
Conditions
Interventions
Group A:5 minutes after delivery, the fetus was given intravenous esticketamine 0.125mg/kg. Postoperative intravenous analgesia pump: butorphenol 0.125mg/kg+ ondansetron 8mg plus normal saline was con
Group B:Esticketamine 0.125mg/kg was given intravenously 5 minutes after delivery. Postoperative analgesia pump: esticketamine 1mg/kg+ Butorphenol 0.125mg/kg+ ondansetron 8mg plus normal saline was co
Group C:5 minutes after delivery, the fetus was given 0.25mg/kg esticketamine intravenously. Postoperative intravenous analgesia pump: butorphenol 0.125mg/kg+ ondansetron 8mg plus normal saline was co
Group D:5 minutes after delivery, the fetus was given 0.25mg/kg esticketamine intravenously. Postoperative analgesia pump: esticketamine 1mg/kg+ butorphanol 0.125mg/kg+ ondansetron 8mg plus normal sal
Group E:Esketamine is not used. Postoperative intravenous analgesic pump: Butorphanol 0.125mg/kg+ ondansetron 8mg + normal saline was configured to 100mL
Sponsors
Xi 'an International Medical Center Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Aged 20-50 years; 2. ASA I-II; 3. Gestation > 28 weeks: 4. Postoperative analgesia treatment is required; 5. Cesarean section in our hospital; 6. Agree to participate in the study and sign the agreement.
Exclusion criteria
Exclusion criteria: 1. Patients with serious cardiovascular and cerebrovascular diseases, serious liver and kidney dysfunction and other important organ failure; 2. Allergic to opioids, sedative-hypnotic drugs, or psychotropic drugs or a history of such drugs abuse: 3. Communication disorders or mental disorders; 4. The investigator considers it unsuitable for this clinical investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Edinburgh Postnatal Depression Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index, PSQI;Vital signs;Numeric Rating Scale (NRS) for pain ;PCA frequency of postoperative analgesia pump; | — |
Countries
China
Contacts
Public ContactWang Binrong
Xi 'an International Medical Center Hospital
Outcome results
None listed