Effects of birth and feeding patterns on intestinal microflora, bifidobacterium community composition and immune homeostasis in infants

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200064858

Enrollment

Unknown

Registered

2022-10-20

Start date

2022-10-30

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Breastfeeding+Vaginal delivery group:none

Breastfeeding+Caesarean section group:none

Milk powder feeding+Caesarean section group:none

Milk powder feeding+Vaginal delivery group:none

Mixed feeding+Vaginal delivery group:none

Mixed feeding+Caesarean section group:none

Eligibility

Sex/Gender

All

Age

No minimum to 1 Years

Inclusion criteria

Inclusion criteria: Infants of 0-4 months old, regardless of gender, mode of production and feeding mode.

Exclusion criteria

Exclusion criteria: 1. Premature birth, intrauterine infection and diseases related to gastrointestinal function; 2. The mother has gestational diabetes mellitus, hypertension, coronary heart disease, acute infectious diseases (especially tuberculosis, viral hepatitis, HIV infection), cancer, postpartum depression, nipples or mastitis; 3. Unable to communicate and answer the questionnaire; 4. Participating in nutrition or drug intervention studies; 5. Infants and mothers were given any antibiotic and commercial probiotic products within one month prior to enrollment.

Design outcomes

Primary

Measure	Time frame
Intestinal flora;	—

Secondary

Measure	Time frame
Cytokine;	—

Countries

China

Contacts

Public ContactLin Yugui

Zhongshan Boai Hospital

18324180870@163.com+86 18324180870

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026