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Study on the application of pronase in the screening of early cancers of the upper gastrointestinal tract

Study on the application of pronase in the screening of early cancers of the upper gastrointestinal tract

Status
Recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200064855
Enrollment
Unknown
Registered
2022-10-20
Start date
2022-11-01
Completion date
Unknown
Last updated
2023-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

early gastric cancer

Interventions

Gold Standard:Pathological biopsy specimen results
Index test:Detection rate of early carcinogenesis using Streptomyces proteinase

Sponsors

Wuwei Cancer Hospital of Gansu Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 69 Years

Inclusion criteria

Inclusion criteria: 1. Patients without gastroscopy contraindications and able to cooperate with the gastroscopic procedure; 2. Patients who are able to stop taking anticoagulant drugs one week before undergoing endoscopy; 3. Patients who voluntarily participate and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with severe heart disease and heart failure; 2. Patients with severe respiratory diseases; 3. Patients with posterior pharyngeal abscess and severe spinal deformity; 4. Patients with other serious diseases or physical weakness who could not tolerate endoscopy; 5. Patients with bleeding tendency; 6. Acute corrosive inflammation of upper digestive tract or suspected perforation of upper digestive tract; 7. Pregnant patients; 8. Patients with iodine allergy history.

Design outcomes

Primary

MeasureTime frame
Endoscopic visibility;Early cancer detection rate;

Secondary

MeasureTime frame
Adverse reaction;

Countries

China

Contacts

Public ContactWu Zhengqi

Wuwei Cancer Hospital of Gansu Province

wwzlwzq@163.com+86 18993536989

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026