Skip to content

A comparative study of the use of platelet-rich plasma in total knee arthroplasty

A comparative study of the use of platelet-rich plasma in total knee arthroplasty

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064839
Enrollment
Unknown
Registered
2022-10-19
Start date
2022-10-19
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

PRP spraying group:PRP spraying
Control group:Saline and thrombin

Sponsors

Qianxi'nan People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
55 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Unilateral knee osteoarthritis was diagnosed according to relevant diagnostic criteria and failed to be treated by conservative treatment; 2. TKA is required and it is the first TKA; 3. Complete clinical data; 4. Aged >=55 years; 5. Agree to participate in this clinical trial and have signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with language, cognitive and communication disabilities; 2. Accompanied by neuropsychiatric diseases; 3. Patients with other joint dysfunction of lower limbs; 4. Combined with rheumatoid arthritis, systemic lupus erythematosus and other rheumatic immune diseases; 5. Patients with severe heart and lung diseases, liver and kidney insufficiency, malignant tumors and other diseases cannot tolerate surgery; 6. Previous history of knee surgery; 7. Patients with severe coagulation dysfunction; 8. Patients with uncontrolled infection; 9. Those who have recently had a heart-brain event.

Design outcomes

Primary

MeasureTime frame
Hospital for Special Surgery Knee Score (HSS);

Secondary

MeasureTime frame
Visual Analogue Scale (VAS) for Pain ;Knee range of motion ;

Countries

China

Contacts

Public ContactWu Jun

Qian Xi Nan People's Hospital

1741405625@qq.com+86 859 3299439

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026