Sleep bruxism
Conditions
Interventions
group A :Placebo intervention + methazolamide intervention at least 48 hours after placebo intervention
group B :Methazolamide intervention + placebo intervention at least 48 hours after methazolamide intervention
Sponsors
Jiangxi Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Adults aged 18-35 years, no gender limit; 2. Meet the following criteria for sleep bruxism: (1) Teeth bruxism at least three times per week in the past six months; (2) Complain of facial muscle pain, weakness or other facial discomfort when getting up in the morning; (3) There is tooth wear; (4) Hypertrophy of masseter or temporalis muscle; 3. The results of polysomnography meet the diagnostic criteria of sleep bruxism set by the American Academy of Sleep Medicine.
Exclusion criteria
Exclusion criteria: 1. Any sleep disorders other than sleep bruxism, such as obstructive sleep apnea syndrome, restless leg syndrome, insomnia, REM sleep behavior disorder, etc.; 2. Have a history of neurological diseases or mental illness; 3. Medication taken within one month before or during the trial for full night polysomnography; 4. Smokers and alcoholics; 5. Stimulant beverages (coffee, tea, etc.) were consumed on the day of the experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total number of oral movements;Number and frequency of different types of sleep bruxism and clusters of sleep bruxism;The number and frequency of sleep bruxism and clusters of sleep bruxism in each sleep period;The number and frequency of isolated limb movements, isolated sleep bruxism and sleep bruxism with limb movements during sleep period;Heart rate and heart rate variability associated with sleep bruxism; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total sleep time, sleep efficiency and sleep latency;The number and frequency of arousal;The proportion of each sleep period;Heart rate and heart rate variability in each sleep period;Sleep periodic limb movement index;Obstructive sleep apnea hypopnea index; | — |
Countries
China
Contacts
Public ContactYao Dongyuan
Jiangxi Provincial People's Hospital
Outcome results
None listed