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Observation of biological rhythms and prediction of optimal rehabilitative time of day in convalescent ischemic stroke patients

Observation of biological rhythms and prediction of optimal rehabilitative time of day in convalescent ischemic stroke patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200064822
Enrollment
Unknown
Registered
2022-10-19
Start date
2022-11-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Sponsors

China Rehabilitation Research Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria of experimental group: (1) Patients sign informed consent; (2) First onset internal carotid artery infarction ischemic stroke confirmed by imaging (MRI); (3) The duration of prestroke was 14-60 days; (4) Aged 18-80 years; (5) The degree of limb motor dysfunction: Brunnstrom stage 2-4; (6) Be able to follow all study procedures and participate in all treatments and evaluations. 2. Inclusion criteria of control group: (1) Gender and age matched with experimental group; (2) Healthy body, regular work and rest; (3) Informed consent.

Exclusion criteria

Exclusion criteria: 1. Exclusion criteria of experimental group: (1) There are contraindications for MRI examination (e.g., there is iron metal in the patient, or cardiac pacemaker, etc.); (2) Major depression (e.g., Hamilton Depression Scale (HAMD) more than 17 points; Geriatric depression scale score greater than 10 points); (3) Severe cognitive dysfunction (e.g., Montreal Cognitive Assessment =2 site amputation, etc.); (7) There are communication defects, which affect research participation; (8) Unable or unwilling to undergo the study procedure or treatment, or the patient may not comply with the study procedure; (9) Life expectancy <6 months; (10) Pregnancy. Labeling: Since the Montreal Cognitive Assessment (MoCA) scale is difficult to interpret for aphasia patients, the exclusion criteria (3) can be waived at the discretion of the lead investigator ('' MoCA score cannot be <22 ''). 2. Exclusion criteria for control group: (1) History of stroke; (2) Sleep disorders such as insomnia and sleep apnea exist; (3) Those who are or have long been engaged in night shift or shift work, or need to shift frequently; (4) Have the habit of staying up late and other irregular work and rest.

Design outcomes

Primary

MeasureTime frame
grip strength;muscle strength;

Secondary

MeasureTime frame
muscle tone;body temperature;blood pressure;response time;

Countries

China

Contacts

Public ContactCheng Lingna

China Rehabilitation Research Center

13439418389@163.com+86 13439418389

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026