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Clinical effect and mechanism of modified Shenling Baizhu powder on peritoneal dialysis

Clinical effect and mechanism of modified Shenling Baizhu powder on peritoneal dialysis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064821
Enrollment
Unknown
Registered
2022-10-19
Start date
2022-11-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Experimental group:Modified Shenling Baizhu Powder
Control group:Clostridium Butyricum and Bifidobacterium Capsule

Sponsors

The First Affiliated Hospital of Anhui University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18~70 years; 2. Patients with renal failure who underwent CAPD and had stable dialysis for more than 6 months; 3. Conform to the syndrome differentiation standard of spleen deficiency and blood stasis syndrome in Chinese medicine; 4. Meet the diagnostic criteria of functional gastrointestinal diseases; 5. The patient agreed to join the study and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients receiving hemodialysis treatment simultaneously; 2. Severe primary diseases such as active malignant tumors, decompensated cirrhosis or hematopoietic system; 3. Abdominal infection occurred within 3 months before the collection of indicators; 4. Severe arrhythmias, severe heart failure, NYHA grade ? or above (New York Heart Association grade ? or ? evidence), or myocardial infarction or cerebrovascular events in the 3 months prior to inclusion.

Design outcomes

Primary

MeasureTime frame
Pepsinogen I;Pepsinogen ?;Gastrin;Motilin;Somatostatin;Cholecystokinin;Vasoactive intestinal peptide;Pancreatic polypeptide;Intestinal flora;

Secondary

MeasureTime frame
Albumin;Leptin;Interleukin 10;Interleukin 18;

Countries

China

Contacts

Public ContactLyu Yong

Department of Nephrology, the First Affiliated Hospital of Anhui University of Chinese Medicine

lvyong0122@163.com+86 13075580983

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026