chronic insomnia
Conditions
Interventions
Single point treatment group:Acupuncture EX-HN1
Acupuncture EX-HN1 and matching points group:Acupuncture EX-HN1 and matching points
Drug control group:Sulforaphane (eszopiclone) tablets
Healthy control group:None
Sponsors
Guang'anmen Hospital China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 55 Years
Inclusion criteria
Inclusion criteria: The treatment group met the following 1,2,3,4,5,6,7 conditions; healthy subjects met 1,4,5,7 conditions: 1. Aged between 40 and 55 years, non-pregnant and lactating females; 2. Meeting the ICSD-3 diagnostic criteria: difficulty in falling asleep; difficulty in maintaining sleep; early awakening and difficulty in falling back asleep; 3. Insomnia of 3-6 months duration; no relevant treatment within the last 2 weeks; 4. Previous health, no major anxiety and depression and cognitive impairment, no history of psychiatric disorders, no myasthenia gravis, no tumor, no serious underlying pathology such as heart, liver and kidney; 5. No metal in the body and no contraindication to MRI; 6. In line with the TCM classification: liver qi stagnation, liver depression and spleen deficiency type insomnia. Symptoms: insomnia for a long time, difficulty in falling asleep, difficulty in falling asleep after waking up, tiredness and fatigue, irritability, irritability, dizziness or headache, drowsiness, abdominal fullness, bitterness in the mouth, sighing, dry or loose stools, thin or yellow tongue coating, teeth marks on the side, string or moist pulse; 7. Agree to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Somatic diseases such as central nervous system disease, substance abuse, alcohol abuse, cardiovascular disease; 2. Other chronic diseases that may affect cognitive function; 3. History of mental illness and family history; 4. People with claustrophobia; people with metal residues in the body, deep vein placement, etc., who cannot perform MRI scans or affect image quality.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain function;Intracerebral metabolites; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical scale; | — |
Countries
China
Contacts
Public ContactLiu Chunling
Guang'anmen Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed