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Clinical study on the efficacy and safety of loquat seed extract for freckle whitening

Clinical study on the efficacy and safety of loquat seed extract for freckle whitening

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064796
Enrollment
Unknown
Registered
2022-10-18
Start date
2022-10-15
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

facial pigmentation

Interventions

Intervention group:Eriobotrya japonica seed water extract
Conrol group:Blank matrix

Sponsors

Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. 12 healthy subjects aged 18-60 years ; 2. There is at least one symmetrical brown pigmented patch on each side of the skin of the test area, and the diameter is not less than 3mm ( not freckles, pigmented nevus, zygomatic brownish nevus ). 3. Voluntary signing of informed consent.

Exclusion criteria

Exclusion criteria: 1. Individuals with severe systemic diseases or other skin conditions; 2. Individuals with a history of severe skin allergies; 3. Those who have received any form of facial skin treatment, fruit acid, laser or cosmetic surgery within the past month, and may have been exposed to ultraviolet radiation for a long time during the trial period (such as travel or vacation), resulting in increased exposure to sunlight; 4. Those who have applied any anti-inflammatory drugs to the test site within the past month; 5. Participants in drug clinical trials or other cosmetic efficacy evaluations within the past month; 6. Pregnant or lactating women; 7. Non volunteer participants or those who are unable to complete the required content according to the experimental requirements.

Design outcomes

Primary

MeasureTime frame
complexion;Skin melanin content; Proportion of surface stains;Proportion of deep stains;

Secondary

MeasureTime frame
Skin heme content;

Countries

China

Contacts

Public ContactHuang Jianmei

Beijing University of Chinese Medicine

hjm70@139.com+86 13671212871

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026