facial pigmentation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. 12 healthy subjects aged 18-60 years ; 2. There is at least one symmetrical brown pigmented patch on each side of the skin of the test area, and the diameter is not less than 3mm ( not freckles, pigmented nevus, zygomatic brownish nevus ). 3. Voluntary signing of informed consent.
Exclusion criteria
Exclusion criteria: 1. Individuals with severe systemic diseases or other skin conditions; 2. Individuals with a history of severe skin allergies; 3. Those who have received any form of facial skin treatment, fruit acid, laser or cosmetic surgery within the past month, and may have been exposed to ultraviolet radiation for a long time during the trial period (such as travel or vacation), resulting in increased exposure to sunlight; 4. Those who have applied any anti-inflammatory drugs to the test site within the past month; 5. Participants in drug clinical trials or other cosmetic efficacy evaluations within the past month; 6. Pregnant or lactating women; 7. Non volunteer participants or those who are unable to complete the required content according to the experimental requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| complexion;Skin melanin content; Proportion of surface stains;Proportion of deep stains; | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin heme content; | — |
Countries
China
Contacts
Beijing University of Chinese Medicine