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Effect of intravenous esketamine on perioperative stress response in gynecological laparoscopic surgery

Effect of intravenous esketamine on perioperative stress response in gynecological endoscopic surgery: a prospective, double-blind, randomized controlled trial

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064787
Enrollment
Unknown
Registered
2022-10-17
Start date
2022-10-13
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecologic endoscopic surgery

Interventions

Sponsors

Guangdong Medical University Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. ASA Level I-II; 2. Age range: 20-60 years old; 3. No serious liver, kidney, lung, or cardiovascular diseases; 4. Not taking benzodiazepine and opioid analgesics for a long time; 5. Female patients who choose to undergo gynecological endoscopic surgery; 6. Agree to participate in this study.

Exclusion criteria

Exclusion criteria: 1. ASA classification>=Level III; 2. Existence of coronary artery disease, unstable hypertension, and abnormal liver and kidney function; 3. Untreated history of hyperthyroidism; 4. Have a history of chronic pain or long-term use of analgesics; 5. Having mental illness or inability to cooperate and communication difficulties; 6. Those with contraindications to ketamine or a history of allergies to ketamine and opioid drugs; 7. Patients who cannot be contacted based on the contact information provided by the patient.

Design outcomes

Primary

MeasureTime frame
IL-6;

Countries

China

Contacts

Public ContactLuyan

Guangdong Medical University Affiliated Hospital

1782639185@qq.com+86 17703092992

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026