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A randomized and controlled clinical study of Lianhua Qingke in the treatment of novel coronavirus pneumonia

A randomized and controlled clinical study of Lianhua Qingke in the treatment of novel coronavirus pneumonia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064767
Enrollment
Unknown
Registered
2022-10-17
Start date
2022-10-14
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19

Interventions

Intervention Group:Conventional therapy+Lianhua Qingke Tablets, 4 tablets/time, 3 times a day
Control group:Conventional therapy

Sponsors

Xingtai People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with novel coronavirus pneumonia diagnosed by etiology test; 2. Age above 18 (inclusive), male or female; 3. Any of the main symptoms (fever, cough, expectoration, sore throat, dry throat) at the time of admission; 4. Sign the written informed consent voluntarily before the start of the study.

Exclusion criteria

Exclusion criteria: 1. There is clear evidence of bacterial infection in respiratory tract infections caused by basic diseases such as primary immunodeficiency disease, acquired immunodeficiency syndrome, congenital respiratory malformation, congenital heart disease, gastroesophageal reflux disease, and pulmonary dysplasia 2. Subjects with the following conditions: asthma requiring daily treatment, any other chronic respiratory disease, respiratory system bacterial infection such as suppurative tonsillitis, acute tracheobronchitis, sinusitis, otitis media and other respiratory diseases that affect clinical trial evaluation. Chest CT confirmed the presence of severe pulmonary interstitial disease, bronchiectasis and other basic lung diseases 3. Severe pneumonia requiring mechanical ventilation 4. According to the judgment of the investigator, the patient may suffer from diseases that may affect the patient's participation in the trial or the outcome of the study, including malignant diseases, autoimmune diseases, liver and kidney diseases, blood diseases, nervous system diseases, and endocrine diseases; Now he has diseases that seriously affect the immune system, such as human immunodeficiency virus (HIV) infection, or the blood system, or splenectomy, organ transplantation, etc 5. Pregnant women or lactating women; 6. Patients who have participated in other clinical trials in the past three months; 7. Allergic constitution, such as those who have a history of allergy to two or more drugs or food, or who are known to be allergic to the ingredients of this drug; 8. The investigator believes that there are any factors that are not suitable for inclusion or affect the efficacy evaluation of the subject.

Design outcomes

Primary

MeasureTime frame
The disappearance rate and median time of clinical symptoms;

Secondary

MeasureTime frame
Single symptom disappearance rate and main symptom disappearance time;Proportion of converting to ordinary type;Proportion of aggravation during treatment;Time and rate of first nucleic acid turning negative;

Countries

China

Contacts

Public ContactZhiguo Gao

Xingtai People's Hospital

283913862@qq.com+86 13191845064

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026