Volume-controlled reperfusion method in patients with acute ST-segment elevation myocardial infarction during primary percutaneous coronary intervention, phase II study

Volume-controlled reperfusion method in patients with acute ST-segment elevation myocardial infarction during primary percutaneous coronary intervention, phase II study - Volume-controlled reperfusion method in patients with acute ST-segment elevation myocardial infarction during primary percutaneous coronary intervention, phase II study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200064755

Enrollment

Unknown

Registered

2022-10-17

Start date

2022-10-18

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infarctioin

Interventions

Volume-Controlled Reperfusion Group:Volume-Controlled Reperfusion followed by rutine PCI

Routine PCI Group:Routine PCI

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 75 years; 2. The initial attack of STEMI; 3. The onset time < 12 h; 4. Proximal occlusion of the dominant coronary artery; 5. TIMI flow grade 0-1.

Exclusion criteria

Exclusion criteria: 1. Previous myocardial infarction; 2. Previous PCI and CABG; 3. Left main coronary artery disease, server multi-vessel disease or server calcification; 4. Cardiogenic shock ( > C); 5. Killip > I; 6. Mechanical complications such as cardiac rupture, ventricular septal perforation or papillary muscle rupture; 7. Complicated with pericardium or congenital heart disease; 8. Complicated with chronic kidney disease, tumor, severe peripheral vascular disease or other serious organic diseases; 9. Patients who cannot complete cardiac MRI examination, such as orthopedic plate implantation, non-nuclear resistant pacemaker, allergic to gadolinium contrast medium.

Design outcomes

Primary

Measure	Time frame
Microvascular obstruction (MVO);	—

Secondary

Measure	Time frame
intramyocardial hemorrhage (IMH);Major adverse cardiac event;TIMI blood flow;In-hospital blood pressure variation;	—

Countries

China

Contacts

Public ContactWang Lefeng

Beijing Chao-Yang Hospital, Capital Medical University

drwlf311@sina.com+86 13601255020

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026