biliary atresia
Conditions
Interventions
Gold Standard:Biliary tract exploration
Index test:serum MMP-7, ultrasound of liver and bile duct and gallbladder,combined diagnostic model based on serum MMP-7,diagnostic accuracy, diagnostic sensitivity, diagnostic specificity, positive p
Sponsors
Chengdu Women's and Children's Central Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age:=17umol/L; Alternatively, serum total bilirubin>=85umol/L, but direct bilirubin accounts for more than 20% of total bilirubin; 3. Pregnancy>=28 weeks, birth weight>=1000g; 4. Sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. It is impossible to complete the sampling before the gold standard diagnosis; 2. Give up further diagnosis and treatment, unable to obtain a definite diagnosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum MMP-7;ultrasound of liver and bile duct and gallbladder;combined diagnostic model based on serum MMP-7;diagnosis sensitivity;diagnosis specificity;Accuracy of diagnosis;Positive predictive value;Negative predictive value; | — |
Countries
China
Contacts
Public ContactMin Du
Chengdu Women's and Children's Central Hospital,
Outcome results
None listed