Early gastrointestinal cancer
Conditions
Interventions
Test:water washing
Conrol group:Standard ESD
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age>18 years old and < 80 years; 2. Normal preoperative body temperature; 3. Preoperative colonoscopy or endoscopic ultrasound assessment is suitable for patients undergoing ESD; 4. Endoscopic examination of mucosal lesions with a size greater than or equal to 2cm; 5. There is no concomitant organic disease of the colon and rectum; 6. Single ESD resection of a single lesion; 7. Patients or family members who understand the research protocol and are willing to participate in this study provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. Under the microscope, it is determined to be a pedunculated polyp; 2. Circumferential lesions; 3. Individuals with low immunity or those undergoing immunosuppressive therapy; 4. Patients with concurrent organic colorectal diseases and intestinal diseases; 5. Patients with familial polyposis; 6. Patients with a history of previous colorectal surgery that may affect the outcome of this surgery; 7. Pregnant or lactating women: 8. Patients with severe emphysema, interstitial pneumonia, or ischemic heart disease who cannot tolerate anesthesia and surgery; 9. The patient has contraindications for ESD surgery; 10. Patients or family members are unable to understand the conditions and objectives of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PEECS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative bleeding perforation;VAS score;Postoperative laboratory examination;Postoperative hospital stay;Postoperative maximum body temperature; | — |
Countries
China
Contacts
Public ContactZhong Yunshi
Zhongshan Hospital, Fudan University
Outcome results
None listed