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Effect of transcutaneous electrical nerve stimulation combined with transcranial direct current stimulation in Chinese patients with mild knee osteoarthritis —— a randomized double-blind controlled trial

Effect of transcutaneous electrical nerve stimulation combined with transcranial direct current stimulation in Chinese patients with mild knee osteoarthritis —— a randomized double-blind controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064735
Enrollment
Unknown
Registered
2022-10-15
Start date
2022-10-15
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

Experimental group:Transcutaneous electrical nerve stimulation combined with sham transcranial direct current stimulation
Control group:Transcutaneous electrical nerve stimulation combined with transcranial direct current stimulation

Sponsors

Dushu Lake Hospital affiliated to Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. People with mild KOA; 2. Age between 60-70 years; 3. Conscious and had full capacity for civil conduct; 4. Subjects who were willing to cooperate with the trial.

Exclusion criteria

Exclusion criteria: 1. Patients undergoing physical therapy or surgery; 2. Those who experience more severe pain in other parts of the body than in the knee joint, and whose physical activity is severely hindered; 3. Patients who use life-sustaining drugs; 4. Subjects who did not sign an informed consent form or were deemed ineligible to participate in this experiment; 5. Patients with contraindications for intervention: a. Patients who have undergone tibial osteotomy, artificial joint replacement, and infectious knee joint disease; b. Patients who have received intra-articular hormone or sodium hyaluronate injections within the past three months; c. Patients with knee joint sensory disorders caused by tumors/knee joint hyperosteogeny/lower limb vascular diseases/rheumatoid arthritis/acute periarthritis of the knee joint (including knee joint OA and inflammatory rheumatoid arthritis)/purulent arthritis, fractures or unilateral meniscus injuries/acute sports knee joint injuries; d. Patients with acute or chronic uncompensated diseases (such as uncontrolled hypertension, chronic obstructive pulmonary disease, heart disease, heart failure or diabetes), epilepsy, skin diseases, etc; e. Equipped with brain medical devices or implanted brain metal devices, or having used life-saving medical electronic devices such as pacemakers, artificial hearts/lungs, or using wearable medical electronic devices; f. Prohibit having cognitive impairment, severe depression, or a history of syncope; g. Allergic constitution and pregnant women are prohibited.

Design outcomes

Primary

MeasureTime frame
Visual Analog Scale;Step length;Cadence;6-minute walk test;Range of motion;Quadriceps strength;

Secondary

MeasureTime frame
Short Form-36 Health Survey;

Countries

China

Contacts

Public ContactMin Su

Dushu Lake Hospital affiliated to Soochow University

sumin@suda.edu.cn+86 512 65223637

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026