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Brain function changes in children with OSAHS by resting-state fMRI

Brain function changes in children with OSAHS by resting-state fMRI

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200064724
Enrollment
Unknown
Registered
2022-10-15
Start date
2022-10-10
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

OSAHS

Interventions

children with OSAHS:none

Sponsors

Shanghai Stomatological Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Children's group: 1. Age 7-14 years old; 2. Diagnosed by a clinical doctor as a child with oral breathing; 3. It was diagnosed as OSAHS by PSG, the obstructive apnea hypopnea index (OAHI) was>1 time/h, and the lowest oxygen saturation (LSaO2) was<=92%; 4. Right-handed; 5. Can cooperate with inspection. Control group: 1. Age 7-14 years old; 2. No oral breathing symptoms recorded by clinical doctors; 3. The patient self reported and confirmed by their family that the nasal cavity is unobstructed, there is no nocturnal sleep snoring, no symptoms of apnea, and no upper respiratory or pulmonary diseases; 4. Right-handed; 5. Can cooperate with inspection.

Exclusion criteria

Exclusion criteria: 1. Complicated with diabetes, serious cardiovascular, cerebrovascular and respiratory diseases and other systemic diseases; 2. Having neurological or psychiatric disorders; 3. Conventional MRI scans show brain parenchymal lesions (such as tumors, cerebral infarction, and cysts); 4. There are contraindications for MRI scanning.

Design outcomes

Primary

MeasureTime frame
brain function;

Countries

China

Contacts

Public ContactYaqiong Zhang

Shanghai Stomatological Hospital, Fudan University

alazia@163.com+86 17710927083

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026