schizophrenia
Conditions
Interventions
Olanzapine group:Take olanzapine
Olanzapine+CLMD group:take Olanzapine+CLMD
control group:no
Chaihu group:take Chaihu
Sponsors
Hunan Brain Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for schizophrenia in ICD-10; 2. Age 18-60 years; 3. Patients and their families fully understand the research project and are willing to participate in the entire experiment; 4. Have not taken any antipsychotic drugs or traditional Chinese medicine within one month prior to enrollment, and have not received electroconvulsive therapy without convulsions in the past; 5. The legal guardian signs a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those who cannot comply with research requirements; 2. Those with major physical diseases, organic brain diseases, or traumatic brain injury; 3. Those with severe impairment of social function or inability to cooperate due to mental symptoms; 4. Severe heart, liver, and kidney dysfunction; 5. Prepare pregnant, pregnant, or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metabolic group biomarkers;ESR1;mTOR;EIF4E;SMAD4; | — |
Countries
China
Contacts
Public ContactHuang Yahui
Hunan Brain Hospital
Outcome results
None listed