Gastric cancer
Conditions
Interventions
Group DGQ:Dexmedetomidine
Group GQ:General anaesthesia combineQLB
Group G:General anaesthesia only
Sponsors
The Second Hospital, Shandong University
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. All patients or family members signed informed consent; 2. Patients with gastric cancer under general anesthesia combined with costal QLB were selected; 3. All of patients used sufentanil for postoperative analgesia; 4. The age raged from 60-85 years; 5. ASA grade I-III.
Exclusion criteria
Exclusion criteria: 1. Preoperative cognitive impairment; 2. History of severe hypertension or heart disease; 3. Liver and kidney dysfunction; 4. Blood system diseases and abnormal bleeding and coagulation; 5. BMI>30kg/m^2; 6. Distant organ metastasis; 7. Recent use of antidepressants, sedatives or analgesics; 8. Drug allergy; 9. History of previous abdominal surgery; 10. Recent history of radiotherapy and chemotherapy; 11. Intraoperative operation was changed to open operation; 12. In patients undergoing nerve block, there were regional block complications such as puncture site injury, infection and bleeding and local anesthetic poisoning; 13. Failed to complete data collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative cognitive index scale (MMSE); | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative rest pain and activity pain were evaluated by NRS;Postoperative analgesic dosage;Adverse reaction;Out of bed time;Drainage flow;Time for drainage tube extraction; | — |
Countries
China
Contacts
Public ContactChang Feng
The Second Hospital, Shandong University
Outcome results
None listed