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Clinical study on the safety and effectiveness of catgut embedding at acupoints in preventing postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: a single center, prospective, randomized, double-blind, controlled study

Clinical study on the safety and effectiveness of catgut embedding at acupoints in preventing postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: a single center, prospective, randomized, double-blind, controlled study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064696
Enrollment
Unknown
Registered
2022-10-14
Start date
2022-10-15
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting

Interventions

Catgut embedding group:Catgut embedding at acupoints
False Catgut embedding group:False Catgut embedding

Sponsors

Shanghai Fourth People's Hospital, School of Medicine, Tongji University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Female; 2. Aged 18-65; 3. ASA classification I-III; 4. Gynecological laparoscopic surgery is planned under general anesthesia; 5. The understanding ability is normal, and the person or his family members can cooperate with the nausea and vomiting evaluation or fill in the questionnaire; 6. Sign the informed consent form voluntarily.

Exclusion criteria

Exclusion criteria: 1. Patients who have taken any antiemetic drugs within 24 hours before operation or have nausea and vomiting symptoms before operation; 2. Severe hypertension, diabetes, coronary heart disease, liver and kidney dysfunction; 3. Difficult intubation during anesthesia induction; 4. Postoperative sedation is required; 5. Those who have contraindications to percutaneous acupoint catgut embedding, such as abnormal coagulation function, scar constitution, local skin damage, infection, etc; 6. Those who have faintness or fear acupuncture treatment; 7. Participated in other clinical trials within 3 months before inclusion in the study; 8. The same patient can only be included once, regardless of whether the cause of the second operation is related to the first cause.

Design outcomes

Primary

MeasureTime frame
Nausea and vomiting;

Secondary

MeasureTime frame
Incidence of complications at the site of wire embedding;Utilization rate of remedial antiemetics 72 hours after operation;Postoperative first exhaust and defecation time;Opioid consumption;VAS pain score within 3 days after operation;Postoperative satisfaction assessment of patients;Postoperative hospital stay;

Countries

China

Contacts

Public ContactCheng Li

Shanghai Fourth People's Hospital, School of Medicine, Tongji University

marklisa@163.com+86 15301705322

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026