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Ultrasound-guided nusinersen administration for spinal muscular atrophy patients with scoliosis: median transverse positioning approach versus paramedian sagittal positioning approach

Ultrasound-guided nusinersen administration for spinal muscular atrophy patients with scoliosis: median transverse positioning approach versus paramedian sagittal positioning approach

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064655
Enrollment
Unknown
Registered
2022-10-13
Start date
2022-10-20
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal muscular atrophy

Interventions

Median transverse positioning group:Median transverse positioning
Paramedian sagittal positioning group:Paramedian sagittal positioning

Sponsors

Qilu Hospital of Shandong University (Qingdao)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. All consented patients were genetic diagnosis confirmed SMA and referred from neurology owing to challenging spinal access.

Exclusion criteria

Exclusion criteria: 1. SMA patients without scoliosis; 2. Contraindications of spine anesthesia, disorder in brain, coagulopathy, local infection, pregnant women, severe cardiopulmonary insufficiency and without available access under US examination.

Design outcomes

Primary

MeasureTime frame
Positioning time;Puncture time;Number of attempts;—

Secondary

MeasureTime frame
Pain scores;—

Countries

China

Contacts

Public ContactZhang Ping

Qilu Hospital of Shandong University (Qingdao)

zpql_2014@126.com+86 18561811770

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026