ARDS
Conditions
Interventions
Intervention Group:iNO
Sponsors
Zhongda Hospital, School of Medicine, Southeast University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old; 2. Diagnosed with moderate or severe ARDS according to the 2012 Berlin definition and received invasive mechanical ventilation.
Exclusion criteria
Exclusion criteria: 1. Absence of informed consent; 2. Prior medical history of lung malignancy, pneumonectomy, and lung transplantation; 3. Presence of pneumatic injuries including pneumothorax, subcutaneous and mediastinal emphysema, closed chest drainage tube, and ventilator monitoring with air leak; 4. Presence of contraindications to EIT monitoring, such as implanted pacemakers; 5. Hemodynamic instability, e.g. increase in vasoactive drugs by more than 30% within 6 hours, or norepinephrine dose exceeding 0.5 mcg/kg/min (temporarily); 6. Expected duration of mechanical ventilation of fewer than 24 hours; 7. Pregnancy and lactation; 8. Need for ECMO treatment; 9. Other conditions that the clinician considers the patient unsuitable for inclusion in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PaO2/FiO2; | — |
Countries
China
Contacts
Public ContactLiu Ling
Zhongda Hospital, School of Medicine, Southeast University
Outcome results
None listed