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Clinical application of opioid-free anesthesia with esketamine in elderly patients undergoing total hip arthroplasty

Clinical application of opioid-free anesthesia with esketamine in elderly patients undergoing total hip arthroplasty

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064648
Enrollment
Unknown
Registered
2022-10-13
Start date
2022-10-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip Arthroplasty

Interventions

EA Group:Esketamine
Conrol group:Fentanyl

Sponsors

Wuxi 9th People’s Hospital Affiliated to Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective Hip Arthroplasty. 2. ASA classification: grade I-III; age: 65-85 years; BMI <25kg/m2.

Exclusion criteria

Exclusion criteria: 1. Preoperative unconsciousness, or inability to provide informed consent and communication difficulties; 2. Those with relevant drug allergies; 3. Patients who refuse to cooperate; 4. Patients with severe cardiopulmonary disease or cranio-cerebral injury and mental illness; 5. Patients with uncontrolled hypertension.

Design outcomes

Primary

MeasureTime frame
Incidence of postoperative delirium;—

Secondary

MeasureTime frame
VAS score 3 days after surgery;MMSE examination scale score 7 days postoperative;Postoperative adverse reactions;NSE, S-100ß serum concentration;—

Countries

China

Contacts

Public ContactHao Hua

Wuxi 9th People’s Hospital Affiliated to Soochow University

55699359@qq.com+86 15861577570

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026