Postoperative Delirium
Conditions
Interventions
Intervention group:Anesthetic "depth" management by DSA and SEF
Control group:Anesthetic "depth" management by PSI index
Sponsors
The Fourth Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 60 years; 2. ASA Physical Score II-III; 3. Scheduled to undergo elective off-pump coronary artery bypass surgery under general anesthesia; 4. Scheduled to stay in hospital for > 5 days after surgery.
Exclusion criteria
Exclusion criteria: 1. Refuse to participate; 2. Emergent surgery; 3. Trauma patients; 4. Preoperative cognitive impairment characterized by Mini-Mental State Examination (MMSE) of 23 or less; 5. Preoperative history of stroke, schizophrenia, major depression, Parkinson's disease, epilepsy, or dementia; 6. Inability to communicate in the preoperative period due to illiteracy, language difficulties, or significant hearing or visual impairment; 7. Inability to complete MMSE and delirium survey; 8. Severe hepatic dysfunction being evaluated for liver transplantation or with a Child- Pugh Class C classification; 9. Severe renal dysfunction requiring renal replacement therapy before surgery; 10. Those who are unlikely to survive for more than 3 days after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of Hospital Stay;Length of ICU stay;Non-delirium Complications; | — |
Countries
China
Contacts
Public ContactSihua Qi
The Fourth Affiliated Hospital of Harbin Medical University
Outcome results
None listed