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Clinical Observation of Modified Yangjing Zhongyu Decotion in treating Hypomenorrhea (Decreased Ovarian Reserve) with Liver and Kidney Yin Deficiency Syndrome

Clinical Observation of Modified Yangjing Zhongyu Decotion in treating Hypomenorrhea (Decreased Ovarian Reserve) with Liver and Kidney Yin Deficiency Syndrome

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064625
Enrollment
Unknown
Registered
2022-10-13
Start date
2022-10-15
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypomenorrhea (Diminished Ovarian Reserve)

Interventions

Chinese medicine treatment group:Orally administered granules of the Yangjing Zhongyu Decotion combined with living guidance
Blank control group:Granules of 5% Yangjing Zhongyu Decotion combined with granules of 5% Yangjing Zhongyu Decotion

Sponsors

Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Meet the TCM diagnostic criteria for hypomenorrheaMeet the western diagnostic criteria for decreased ovarian reserve; 2. Meet the TCM diagnostic criteria for liver and kidney yin deficiency syndrome; 3. Age 20-40 years old course >=2 months; 4. Not accept hormone therapy or other therapy for diminished ovarian reserve within one month; 5. Patients who agreed to participate in the trial and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Not used contraceptive tool strictly or had the desire of fertility within half a year; 2. Took food or medicine those are rich in hormone or parahormone like bee milk and soy isoflavone for a long time; 3. With organic disease of reproductive organ; 4. With serious primary disease of heart and cerebral vessels, liver, kidney and hematopoietic system; 5. With premature ovarian failure caused by removing bilateral or unilateral ovaries and chemoradiotherapy; 6. Patients who were allergic to Yangjing Zhongyu Decotion; 7. Psychopath.

Design outcomes

Primary

MeasureTime frame
Serum FSH;Serum LH;Serum E2;

Secondary

MeasureTime frame
Menstrual Blood, MBL;TCM clinical syndrome integral;Routine blood test;Routine urine test;Routine stool test;Liver function;Renal function;Electrocardiogram;

Countries

China

Contacts

Public ContactXu Hongyan

Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University

13683555987@139.com+86 13683555987

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026