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Comparison of the safety and efficacy of tunneled and routine peripherally inserted central catheter under electrocardiography Doppler ultrasound guidance in immunocompromised patients

Comparison of the safety and efficacy of tunneled and routine peripherally inserted central catheter under electrocardiography Doppler ultrasound guidance in immunocompromised patients: A multicenter, prospective, randomized controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064553
Enrollment
Unknown
Registered
2022-10-11
Start date
2022-11-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tunneled peripherally inserted central catheter

Interventions

Experimental group:tunneled peripherally inserted central catheter
Control group:routine peripherally inserted central catheter

Sponsors

Zhongnan Hospital of Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age = 18 years old; 2. Immunocompromised patients, including: (1) Patients with congenital T cell/B cell defects or macrophage disorders; (2) Patients with solid malignant tumors or hematological malignancies; (3) Patients suffering from AIDS; (4) Patients undergoing splenectomy or solid organ transplantation; (5) Patients suffering from rheumatic diseases and treated with immunomodulatory drugs; 3. Follow the doctor's advice for the first time PICC catheterization patients; 4. No serious cardiovascular disease before catheterization, such as atrial fibrillation, pulmonary heart disease, severe conduction block, etc.; 5. Patients who have not participated in other clinical studies; 6. Patients who voluntarily participate in the clinical research and can cooperate with clinical follow-up.

Exclusion criteria

Exclusion criteria: 1. Known allergy to catheter material; 2. A history of infection, injury, or radiation therapy at the puncture site; 3. History of venous thrombosis or surgical operation at the puncture site; 4. Severe abnormal coagulation function; 5. Superior vena cava compression syndrome; 6. Radical mastectomy for breast cancer or axillary lymph node dissection on the operative side of the limb; 7. Pacemaker and arteriovenous fistula ipsilateral limb.

Design outcomes

Primary

MeasureTime frame
Postoperative complications;

Secondary

MeasureTime frame
Catheter indwelling time;unplanned extubation rate;one-time catheterization success rate;patient comfort;

Countries

China

Contacts

Public ContactWei Ding

Zhongnan Hospital of Wuhan University

112992266@qq.com+86 27 67813023

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026