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Comparison of rimazolam and propofol for hysteroscopic surgery under general anesthesia: a randomized crossover trial

Comparison of rimazolam and propofol for hysteroscopic surgery under general anesthesia: a randomized crossover trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200064551
Enrollment
Unknown
Registered
2022-10-11
Start date
2022-10-12
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endometrial cancer

Interventions

Group A:Stage 1: propofol + stage 2: Remazolam
Group B:Stage 1: Remazolam + stage 2: propofol

Sponsors

Obstetrics & Gynecology Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: The patient was between 18 and 40 years of age, had an American Society of Anesthesiologists (ASA) Class I or II body condition, and had a body mass index (BMI) of 19-28 kg/m2.

Exclusion criteria

Exclusion criteria: 1. Patients with difficult airway: modified Mallampati score grade III or IV; 2. Combined with other systemic diseases such as kidney or liver disease; 3. People with severe neuropsychiatric diseases; 4. Patients who took benzodiazepines or opioids every day or intermittently took benzodiazepines in the past 3 months; 5. Those who are allergic or contraindicated to anesthetic drugs; 6. Patients who have difficulty communicating.

Design outcomes

Primary

MeasureTime frame
Bispectral index (BIS) ;Athens Insomnia Scale;Recovery quality scale;

Secondary

MeasureTime frame
modified observer’s assessment of alert;

Countries

China

Contacts

Public ContactYang Chen

Obstetrics & Gynecology Hospital, Fudan University

annie.114@163.com+86 13671667155

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 8, 2026