thyroid disease
Conditions
Interventions
Group 1 :Anesthesia was induced and maintained with ciprofol
Group 2:Anesthesia was induced and maintained with propofol
Sponsors
The First Affiliated Hospital of Ji'nan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. ASA classification I-II; 2. The age is between 18 and 60 years old; 3. Patients undergoing elective endoscopic thyroidectomy; 4. 18 kg/m2 <= Body Mass Index (BMI) <= 28 kg/m2.
Exclusion criteria
Exclusion criteria: 1. Those who have contraindications to general anesthesia or have a history of anesthesia accidents in the past; 2. Those who are known to be allergic to the active ingredients or auxiliary materials of cyclophosphamide or propofol injection; 3. Complicated with other important organ dysfunction: including severe liver and kidney dysfunction, brain organic diseases or serious cardiopulmonary diseases; 4. Uncontrolled diabetes or hypertension; 5. Patients with a past history of abuse of psychotropic drugs or sedative/narcotic drugs; 6. Nervous system dysfunction, mental illness or cognitive dysfunction; 7. Those who have participated in any drug clinical trials within one month before screening; 8. Pregnant and lactating women; 9. Patients who have taken hormones and non-steroidal anti-inflammatory drugs before operation; 10. Other circumstances in which the researcher judges that the patient is not suitable to participate in the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change of hemodynamic fluctuations; | — |
Secondary
| Measure | Time frame |
|---|---|
| change of BIS value;awakening time;monitor the treatment room stay time after postoperative anesthesia;arterial blood gas;postoperative pain;Postoperative sedative score;Incidence of infusion pain;Incidence of vomiting after surgery;Incidence of hyoxenia;incidence of hypotension;intraoperative vasoactive drug dosage;Incidence of restlessness after surgery;Incidence of intraoperative awareness; | — |
Countries
China
Contacts
Public ContactYalan Li
The First Affiliated Hospital of Jinan University
Outcome results
None listed